Abhijeet S. Kate, Ph. D

Ph.D. Florida Atlantic University, USA 2008

Abhijeet S. Kate Ph.D.

Assistant Professor

Tele :+91 9960248296

E-mail : kate.abhi.s@gmail.com

Research Interest:

Implementation of various LC-MS based dereplication strategies to discover novel scaffolds from biological sources such as marine and terrestrial bacteria, fungi and plants. Downstream process optimization for large scale isolation of Natural Products. Fingerprinting of extracts by LC-UV-MS in Natural Products based drug discovery program. Development of novel approaches for the separation and characterization of marine natural products to accelerate the discovery of drug leads

Experience:

  • July 2017 - Present:
    Assistant Professor, NIPER-Ahmedabad, Palaj, Gandhinagar
  • December 2014 – July 2017:
    Senior Scientist, SABIC Research and Technology Center,Bangalore
  • January 2010 –November 2014:
    Group Leader, Piramal Life Science Limited, Mumbai
  • July 2008 – December 2009:
    Application Engineer, Agilent Technologies, Bangalore
  • September 2006 – April 2008:
    Research Associate, University of Prince Edward Island, Charlottetown, PEI, Canada
  • February 2003 – June 2004:
    Group Leader, Enem Nostrum Remedies Pvt. Ltd.,Mumbai
  • July 2000 – January 2003:
    Analytical chemist, Medlar laboratories Pvt. Ltd.,Mumbai

Honours/Awards/Grants/Consultancies:

  • Selected to work on DBT-Piramal funded Mega Project "Screening of Biomolecules from microbial diversity collected from different ecological niches – Part II chemical characterization”
  • Awarded research funding from Florida Atlantic University during Ph.D. program
  • Recipient of "Gold Medal” in Chemistry and "Silver Medal” in Mathematics during B.Sc. (University topper in chemistry and mathematics)

Publications:

  • NFAT-133 increases glucose uptake in L6 myotubes by activating AMPK pathway. Chandni S. Thakkar,Abhijeet S. Kate, Dattatraya C. Desai, Asit Ranjan Ghosh and Asha A. Kulkarni-Almeida., European Journal of Pharmacology,http://dx.doi.org/10.1016/j.ejphar.2015.11.006i,
  • Anti inflammatory properties of mutolide isolated from the fungus Lepidosphaeria species (PM0651419)., Meet Shah, Sunil Kumar Deshmukh, Shilpa A. Verekar, Akash Gohil,Abhijeet S. Kate, V. Rekha and Asha Kulkarni Almeida., SpringerPlus, 4:706, 2015,
  • Anticancer activity of koningic acid and semisynthetic derivatives, Nicolas J. Rahier, Nicolas Molinier, Christophe Long, Sunil Kumar Deshmukh,Abhijeet S. Kate, Prafull Ranadive, Shilpa Amit Verekar, Mangesh Jiotode, Rahul R. Lavhale, Pradipta Tokdar, Arun Balakrishnan, Samuel Meignan, Céline Robichon, Bruno Gomes, Yannick Aussagues, Arnaud Samson, François Sautel and Christian Bailly., Bioorganic & Medicinal Chemistry, 23 (13),2015, pp 3712-3721,
  • A halogenated pseudopterane diterpene from the Bahamian octocoral Pseudopterogorgia acerosa,Abhijeet S. Kate, Kelly Richard, Balaji Ramanathan, and Russell G. Kerr, Can. J. Chem.,2010, 88(4): pp 318–322
  • A Simple and Sensitive APCI-LC-MS Method for the Detection of the Antitumor Agent, Carmustine (BCNU) in Rat Plasma, Abhijeet S. Kate; Amber C. Kohl; Russell G. Kerr, J. of Liq. Chrom. & Related Technologies,2010, 33 (6), pp 818 – 824
  • Isolation, Biomimetic Synthesis, and Cytotoxic Activity of Bis(pseudopterane) Amines.,Abhijeet S. Kate, Jason K. Pearson, Balaji Ramanathan, Kelly Richard and Russell G. Kerr, J. Nat. Prod.,2009, 72 (7), pp 1331–1334.
  • Lipidyl Pseudopteranes A-F: Isolation, Biomimetic Synthesis, and PTP1B Inhibitory Activity of a New Class of Pseudopteranoids from the Gorgonian Pseudopterogorgia acerosa,Abhijeet S. Kate, Isabelle Aubry, Michel L. Tremblay and Russell G. Kerr , J. Nat. Prod., 2008, 71 (12), pp 1977–1982
  • Investigation of the biosynthetic origin of the diterpenes in gorgonian Pseudopterogorgia acerosa., Abdelnasser S.S Ibrahim,Abhijeet Kate, and Russell G. Kerr, JASMR,2008, 3(2): pp 177-185

Book/Book Chapter/Patents/Peer Review Abstract

Patents

  • USE OF A THIOPEPTIDE COMPOUND IN THE TREATMENT OF CLOSTRIDIUM DIFFICILE ASSOCIATED INFECTIONS: Mahajan Girish,Kate Abhijeet, Sudhir, Ranadive Prafull, Chadha Bhupinder Singh, Shouche Yogesh, Purohit Hemant, Balakrishnan Arun, PCT Application No.: PCT/IB2014/065702, 30.10.2014
  • MACROCYCLIC LACTONE DERIVATIVES AND USES THEREOF: HARIHARAN Sivaramakrishnan,Kate Abhijeet Sudhir, THOMAS Becky Mary, KULKARNI-ALMEIDA Asha, TRIVEDI Jacqueline Vinodkumar, JADHAV Mahesh Gundaji, SHAH, Meet, PCT application No. : PCT/IB2014/058693, 31.01.2014
  • NUCLEOSIDE ANALOGUE AS AN ANTICANCER COMPOUND: Kate Abhijeet Sudhir, GEORGE Saji David, SONAWANE Shailendra, PERIYASAMY, Giridharan; PCT Application No.: PCT/IB2013/052481, 03.10.2013
Presentations:
National : 01
International: 02
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