<strong>Akshay Srivastava, PhD

Akshay Srivastava, PhD

Assistant Professor

Tele: +91 79 66745555

Email:akshay.srivastava@niperahm.ac.in

Research Interest

Technological innovation through strong basic knowledge in biological sciences thrive my interest in translational research with the aim of improving public health. I am interested in pursuing translational biomedical research involving fabrication of biomaterial based medical devices, finding novel therapeutic strategies for tissue regeneration and developing in vitro platforms to understand disease pathology. Our group is also focused on developing new methods for the identification and isolation of therapeutic cell types for tissue repair, fabrication of cell and drug delivery platform and designing artificial cellular niches for stem cell homing.

Experience

  • December 2016 – till date
    Assistant professor, National Institute of Pharmaceutical Education and Research, Ahmedabad, Gujrat, India
  • August 2016 – November 2016
    Research Scientist, National Institute of Pharmaceutical Education and Research, Ahmedabad, Gujrat, India
  • May 2013 – April 2016-08-16
    Postdoctoral Research Fellow, Centre for Research in Medical Devices, National University of Ireland Galway, Ireland
  • August 2011 – April 2013
    Postdoctoral Research Fellow, Department of Microbiology & Network of Excellence for Functional Biomaterial, National University of Ireland Galway, Ireland
  • January 2009 – January 2011
    Senior Research Fellow, Department of Biological Sciences and Bioengineering, Indian Institute of Technology Kanpur, India
  • March 2010 – June 2010
    Guest Lecturer, C.S.J.M. University Kanpur, India
  • June 2003 – December 2003
    Lecturer (Ad hoc), C.S.J.M. University Kanpur, India

Honours/Awards/Grants/Consultancies

  • CSIR-UGC National Eligibility test (NET) fellowship. India (2003)
  • Graduate Aptitude Test in Engineering (GATE) India (2003)
  • Best poster presentation at international conference (BIND’06), India (2006)
  • Travel grant from Department of Science and Technology (DST), India (2008)
  • Travel grant from Council of Scientific and Industrial Research (CSIR), India (2008)
  • Travel grant from Council of Scientific and Industrial Research (CSIR), India (2010)
  • Selected for Young India Investigator (YIM-India) meeting held at Pune, India (2012)
  • Reviewer for PLoS One (2013)
  • SYIS-EU chair in TERMIS-EU conference (2014)
  • Science foundation Ireland award for research work in Japan (ISCA) (2015)
  • Certificate of appreciation for my published articles (2007, 2009 and 2010)
  • Academic Incentive Award for publishing high-impact journal papers during PhD (2008)

Publications

  • Akshay Srivastava, Isma Liza Mohd Isa, Peadar Rooney, Abhay Pandit. Bioengineered three-dimensional diseased intervertebral disc model revealed inflammatory crosstalk Biomaterials 2017;123: 127-141.
  • Orla Galvin, Akshay Srivastava, Oliver Carroll, Rajiv Kulkarni, Steve Dykes, Steve Vickers, Keith Dickinson, Rob Jones, Sharon Cheetham, Abhay Pandit, Breandán N. Kennedy. A sustained release formulation of novel quininib-hyaluronan microneedles inhibits angiogenesis and retinal vascular permeability in vivo. Journal of Controlled Release 2016; 233: 198-207.
  • Malgorzata Wronska, Iain O'Connor, Maura Tilbury, Akshay Srivastava and Gerard Wall. Adding functions to biomaterial surfaces through protein incorporation. Advanced Material 2016; 28(27): 5485-5508.
  • Maria J Hortiguela, Lucie, Aumailley, Akshay Srivastava, Claire Cunningham, Soshee Anandakumar, Sylvain Robin, Abhay Pandit, Xuejun Hu, J. Gerard Wall. Engineering recombinant antibodies for polymer biofunctionalization. Polymers for Advanced Technologies 2015; 26(12): 1394-1401
  • Akhilesh Kumar Sakhya, Akshay Srivastava, Ashok Kumar. Polymeric cryogel‐based boronate affinity chromatography for separation of ribonucleic acid from bacterial extracts. Current Protocols in Nucleic Acid Chemistry 2015;10.16. 1-10.16. 10.
  • Sumit Murab, Juhi Samal, Akshay Srivastava, Alok R. Ray, Abhay Pandit, Sourabh Ghosh. Glucosamine loaded injectable silk-in-silk integrated system modulate mechanical properties in bovine ex-vivo degenerated intervertebral disc model. Biomaterials 2015; 55: 64-83
  • Isma Liza Mohd Isa, Akshay Srivastava, David Tiernan, Peter Owens, Peadar Rooney, Peter Dockery, Abhay Pandit. Hyaluronic Acid Based Hydrogels Attenuate Inflammatory Receptors and Neurotrophins in Interleukin-1β Induced Inflammation Model of Nucleus Pulposus Cells. Biomacromolecules 2015; 16(6): 1714–1725
  • Peter Rooney, Akshay Srivastava, Luke Watson, Leo Quinlan, Abhay Pandit. Hyaluronic Acid Decreases IL-6 and IL-8 Secretion and Permeability in an Inflammatory Model of Interstitial Cystitis. Acta Biomaterialia, 2015: 19: 66-75
  • Akshay Srivastava, Claire Cunningham, Abhay Pandit, J. Gerard Wall. Improved gene transfection efficacy and cytocompatability of multifunctional polyamidoamine-cross-linked hyaluronan particles. Macromolecular Bioscience 2015; 15(5): 682-690
  • Gianluca Fontana, Akshay Srivastava, Dilip Thomas, Pierce Lalor, Peter Dockery, Abhay Pandit. A three-dimensional microgel platform for the production of cell factories tailored for the nucleus pulposus. Bioconjugate Chemistry 2015; 26(7): 1297-1306
Complete list

Book/Book Chapter/Patent/Peer Review Abstract

Book Chapters

  • Akshay Srivastava. Chemistry of targeted immobilization of biomediators. In: Functionalised cardiovascular stents (Gerard Wall, Halina Podbielska, Magdalena Wawrzyńska and Laura Overend, Ed.) (in preparation)
  • Akshay Srivastava,Samarjeet Singh, Ashok Kumar. Supermacroporous functional cryogel stationary matrices for efficient cell separation. In: Supermacroporous Cryogel: Biomedical and Biotechnological Applications ( Ashok Kumar, Ed.) CRC Press 2016, pp. 447-466.
  • Akshay Srivastava, Akhilesh Kumar Sakhya, Ashok Kumar, Particulate/cell separations using macroporous monolithic matrices. In: Advanced separations by specialized sorbents (Ecaterina Stela Dragan Ed.) CRC Press (taylor & Fancis) 2014 pp. 69-88
  • Ashok Kumar, Era Jain and Akshay Srivastava. Macroporous polymeric scaffolds for tissue engineering applications. In Macroporous Polymers: Production Properties and Biotechnological/Biomedical Applications (Bo Mattiassson, Ashok Kumar, Igor Yu. Galaev Eds.). CRC Press, Taylor & Francis Group, Boca Raton, USA. 2010 pp. 405-466.
  • Ashok Kumar, Akshay Srivastava and Era Jain. Biomaterial Application. In: Advanced Biomaterials: Fundamentals, Processing and Applications (Bikramjit Basu, Dhirendra Katti and Ashok Kumar, Eds.). John Wiley and sons Inc. (Hoboken, NJ). 2009 pp. 535-550.

Patents

  • Granted : Ashok Kumar, Haider Sami, Akshay Srivastava, Anigmanshu Ghatak. New Device; Cryogel device. Patent no. 0950156-0 (SE Patent)
  • Applied : Ashok Kumar, Akshay Srivastava, Samarjeet Kumar. Cryogel filter device for the separation of leukocytes.
Presentations
National 07
International 07
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