Dr. Aditya sunkaria

PDF UGC DS Kothari Postdoc Fellow, Panjab University,2015

PDF DST Young Scientist, Panjab University ,2017

Ph.D. Postgraduate Institute of Medical Education & Research, Chandigarh 2013

Aditya Sunkaria, PhD

Assistant Professor

Tele : +91 9888125606

E-mail : adityasunkaria@gmail.com ,adityas@niperahm.ac.in

Research Interest

Currently I am working with nutraceuticals to re-activate the diminished proteasome activity in neurodegenerative disorders like Alzheimer’s and Parkinson’s, using rodent as well as tissue culture models. In addition, I am also exploring the role of purinergic receptors involved in microglial migration during postnatal brain development as well as trying to understand the involvement of these cells in organophosphates induced neurodegeneration.

Experience

    • August 2017 – Present
      Assistant Professor, NIPER-Ahmedabad
    • August, 2015 – July, 2017
      DST Young Scientist, Panjab University, Chandigarh
    • March, 2013 – August, 2015:
      DS Kothari Postdoc Fellow, Panjab University, Chandigarh

Honours/Awards/Grants/Consultancies

    Grants

  • International travel grant from Department of Biotechnology (2012)
  • Startup Research grant for young scientists from DST (2015)
  • Dr. DS Kothari Postdoctoral Fellowship (2013)

    Awards

  • CSIR - NET (2007)
  • DBT - JNU Combined MS Biotech Entrance Examination (2005)

Publications

  • Sulforaphane attenuates postnatal proteasome inhibition and improve spatial learning in adult mice.Sunkaria A, Bhardwaj S*, Yadav A*, Halder A, Sandhir R. J Nutr Biochem. 2017 [Accepted]
  • Migration and phagocytic ability of activated microglia during postnatal development is mediated by calcium dependent purinergic signaling.Sunkaria A, Bhardwaj S, Halder A, Yadav A, Sandhir R. Mol Neurobiol. 2016 Mar;53(2):944-54.
  • Evaluation of potential flavonoid inhibitors of glyoxalase-I based on virtual screening and in vitro studies.Sunkaria A, Yadav A, Kumar R, Singhal N, Kumar M, Sandhir R. J Biomol Struct Dyn. 2016 May;34(5):993-1007.
  • 4-Hydroxy TEMPO Attenuates Dichlorvos Induced Microglial Activation and Apoptosis.Sunkaria A, Sharma DR, Wani WY, Gill KD. ACS Chem Neurosci. 2014;5(2):115-27
  • Attenuation of Dichlorvos-Induced Microglial Activation and Neuronal Apoptosis by 4-Hydroxy TEMPO.Sunkaria A, Sharma DR, Wani WY, Gill KD. Mol Neurobiol. 2014;49(1):163-75
  • Dichlorvos Induced Cell Cycle Arrest and DNA Damage Repair Activation in Primary Rat Microglial Cells.Sunkaria A, Wani WY, Sharma DR and Gill KD. J Neuroscience Research. 2013;91(3):444-52
  • Dichlorvos Exposure Results in Activation Induced Apoptotic Cell Death in Primary Rat Microglia.Sunkaria A, Wani WY, Sharma DR, Gill KD. Chem Res Toxicol. 2012;25(8):1762-70
  • Cell cycle activation in p21 dependent pathway: An alternative mechanism of organophosphate induced dopaminergic neurodegeneration. Wani WY, Kandimalla RJ, Sharma DR, Kaushal A, Ruban A,Sunkaria A, Vallamkondu J, Chiarugi A, Reddy PH, Gill KD. Biochim Biophys Acta. 2016 Jun 2. [Epub ahead of print]
  • Quercetin attenuates neuronal death against aluminum-induced neurodegeneration in the rat hippocampus. Sharma DR, Wani WY,Sunkaria A, Kandimalla RJ, Sharma RK, Verma D, Bal A, Gill KD. Neuroscience. 2016 Jun 2;324:163-76.
  • Nano-antioxidants: An emerging strategy for intervention against neurodegenerative conditions. Sandhir R, Yadav A,Sunkaria A, Singhal N. Neurochem Int. 2015 Aug 24. pii: S0197-0186(15)30039-5. doi: 10.1016/j.neuint.2015.08.011. [Epub ahead of print] Review.
Complete list

Books/Book Chapters/Patents/Peer Review -Abstracts

Book Chapters

  • Molecular Mechanisms Involved in the Neuroprotective Action of Phytochemicals.Sunkaria A, Yadav A, Sharma SK, and Sandhir R. Neuroprotective Effects of Phytochemicals in Neurological Disorders, First Edition. 515-559. John Wiley & Sons, Inc.
  • Multifacet Damage by Cadmium: Impaired Reproduction, Endocrine Disruption and Requirement for Novel Biomarkers.Sunkaria A, and Gill KD. Environmental Pollution, Ecology and Human Health: 209-220, NAROSA Publications, New Delhi.

Peer Review Abstract

  • Quercetin Attenuates Aluminum-Induced Apoptosis in Rat Hippocampus, by Preventing Cytochrome c Translocation, Bcl-2 Decrease, Bax Elevation, Caspase-3 and p53 Activation. The 16th Biennial Meeting of the Society for Free Radical Research – International, September 6-9, 2012 at Imperial College London, (UK). Pages S44-S45
  • Protective Effect Of MitoQ Against Dichlorvos Induced Oxidative Stress And Ensuing Dopaminergic Neuronal Cell Death. The 16th Biennial Meeting of the Society for Free Radical Research – International, September 6-9, 2012 at Imperial College London, (UK). Page S107
Presentations:
National : 02
International: 02
Projects:
Ongoing 01
PhD:
Ongoing: 01
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