Anita Mahapatra, Ph. D

PDF University of Pretoria, South Africa 2005

Ph.D. Utkal University 2001

Anita Mahapatra, Ph.D.

Assistant Professor

Tele :+91 79 66745555

E-mail : anita@niperahm.ac.in

Research Interest

Target oriented and lead based design and development of New Chemical Entities (NCEs) of natural scaffolds against Diabetes, TB and Cancer, Discovery of new bioactive leads from natural sources for cancer and neuroprotection, Development of National repository of secondary metabolites

Experience

  • September 2008 - Present:
    Assistant Professor, NIPER-Ahmedabad, Palaj, Gandhinagar
  • June 2006 - September 2008:
    Scientist Fellow, CSIR, Institute of Minerals and Material Technology (formerly RRL), Bhubaneswar, Odisha
  • August 2004 - July 2005:
    Post Doctoral Fellow, University of Pretoria, Pretoria, South Africa
  • June 2003 - May 2006:
    Research Associate, CSIR, Regional Research Laboratory,Bhubaneswar, Odisha
  • November 1997 – May 2003:
    Senior Project Fellow, Regional Research Laboratory, Bhubaneswar, Odisha
  • February 1994 – October 1997:
    Senior Project Assistant, Regional Research Laboratory,Bhubaneswar, Odisha

Honours/Awards/Grants/Consultancies

Awards

  • Best Poster Award at National conference on Herbal drugs: opportunities and challenges, Ahmedabad November (2014)
  • Prof. A.R. Rao Memorial Best Young Researcher Award at International Conference on "Recent Advances in Cancer Research - Therapeutics to Chemoprevention, Ahmedabad February (2012)
  • Dr. P.D. Sethi Award for the Best Research Paper on "Application of TLC/ HPTLC in Pharma, Herbal and other Analysis" (2008)
  • DST Women Scientist Award – Department of Science & Technology, 2003

Publications

  • Anita Mahapatra*, P. Shah, M. Jivrajani and M. Nivsarkar, Synthesis and blastocyst implantation inhibition potential of lupeol derivatives in female mice, Records of Natural Products 9 (4), 561-566. (2015)
  • Anita Mahapatra*, N. Chauhan, D. R. Patel, N. P. Kalia, V. S. Rajput and I. A. Khan, Synthesis and anti-tubercular activity of oleanolic acid analogues, Pharmaceutical Chemistry Journal, 48(1), 39-43. (2014) DOI. 10.1007/s11094-014-1042-6
  • Anita Mahapatra*, V. Maheswari, N. P. Kalia, V. S. Rajput and I. A. Khan, Synthesis and anti-tubercular activity of berberine derivatives, Chemistry of Natural Compounds, 50(2), 321-325. (2014) DOI. 10.1007/s10600-014-0942-8
  • N. Kishore, B. Binneman, Anita Mahapatra, M. van de Venter, D. du Plessis-Stoman, G. Boukes, P. Houghton, J.J.M. Meyer, N. Lall, Cytotoxicity of synthesized 1,4-naphthoquinone analogues on selected human cancer cell lines, (2014) Bioorganic Medicinal Chemistry, 22(17), 5013-5019. DOI. 10.1016/j.bmc.2014.06.013
  • U. V. Mallavadhani, Anita Mahapatra, B. Pattnaik, N. Suri, A. K. Saxena, Synthesis and anti-cancer activity of some novel C-17 analogs of ursolic and oleanolic acids, Medicinal Chemistry Research. 22(3), 1263-1269. (2013) DOI. 10.1007/s00044-012-0106-y
  • Anita Mahapatra, S. P. N. Mativandlela, B. Binneman, P. B. Fourie, Chris J. Hamilton, J. J .M. Meyer, F van der Kooy, P. Houghton and N. Lall, Activity of 7-methyljuglone derivatives against Mycobacterium tuberculosis and as subversive substrates for mycothiol disulfide reductase, Bioorganic Medicinal Chemistry, 15(24), 7638-7646. (2007) DOI. 10.1016/j.bmc.2007.08.064
  • U. V. Mallavadhani, Anita Mahapatra and S. Mohapatra, An efficient chemical method for separation of corsolic acid from its isomeric maslinic acid, Natural Products Research, 20(10), 946-952. (2006) DOI. 10.1080/14786410500463254
  • U. V. Mallavadhani, K. Narasimhan, A.V.S. Sudhakar, Anita Mahapatra, W. Li and R.B. Van Breemen, Three new pentacyclic triterpenes and some flavonoids from the fruits of an Indian ayurvedic plant Dendrophthoe falcata and their estrogen receptor binding activity, Chemical and Pharmaceutical Bulletin, 54(5),740-744. (2006) DOI. 10.1248/cpb.54.740
  • U. V. Mallavadhani, K.V.S. Satyanarayana, Anita Mahapatra, and A.V.S. Sudhakar, A new tetracyclic triterpene from the latex of Euphorbia nerifolia, Natural Products Research, 18(1), 33-37. (2004) DOI.10.1080/105756303 1000122068
  • U. V. Mallavadhani, Anita Mahapatra, S. Sabitha Raja and C. Manjula, Antifeedant activity of some pentacyclic triterpene acids and their fatty ester analogues, Journal of Agricultural and Food Chemistry, 51(7), 1952-1955. (2003) DOI.10.1021/jf020691d
  • U. V. Mallavadhani, Anita K. Panda and Y. R. Rao, Pharmacology and Chemotaxonomy of Diospyros, (1998) Phytochemistry,49(4), 901-951. DOI No.10.1016/S0031-9422(97)01020-0
Complete list

Books/Book Chapters/Patents/Peer Review -Abstracts

Patents

  • U. V. Mallavadhani, A.V.S. Sudhakar and Anita Mahapatra , Single pot process for the regioselective synthesis of neolignan framework from asarones, US Patent No. 7872160; 18/01/2011
  • U. V. Mallavadhani, Anita K. Panda and Y. R. Rao, A process for the preparation of long chain fatty acid esters of ursolic acid as potent anti microbial agents, Patent No. 220524, Granted Date 29.5.2008.
  • U. V. Mallavadhani, Anita K. Panda and Y. R. Rao, A process for the preparation of ursolic acid stearate and oleanolic acid palmitate as potent antifeedants, Patent No. 231039, Granted Date 28.2.2008.

Peer Review Abstract

  • B. Binneman, Anita Mahapatra, J. J. M.Meyer, and N. Lall, Evaluation of medicinal plants and synthesized naphthoquinones on cancer cells, (2007) South African Journal of Botany 73(2), 325. Impact Factor: 1.409 : DOI No.10.1016/j.sajb.2007.02.154
  • T. E. Tshikalange, Anita Mahapatra, J. J. M. Meyer and N. Lall In vitro HIV-1 reverse transcriptase inhibitory activity of naphthoquinones and derivatives from Euclea natalensis, (2007) South African Journal of Botany 73(2), 339. Impact Factor: 1.409 ; DOI No.10.1016/j.sajb.2007.02.200
Presentations:
National : 10
International: 17
Projects:
Completed 11
Ph.D:
Ongoing 01
MS Dissertation:
Completed: 35
Ongoing: 03
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