Dr. Dinesh Kumar

PDF North Dakota State University, ND, USA, 2017

Ph.D. NIPER SAS NAGAR (Mohali), 2013

Dr. Dinesh Kumar

Assistant Professor

Tele : +91-8709447063

E-mail : dinesh.nipera@gmail.com,dineshnandan79@gmail.com

Research Interest

Development of new strategies and concepts in synthetic organic chemistry to address challenging problems in biomedical research, particularly anti-cancer drug discovery.

  • Development of new reaction methodologies
  • Discovery of anti-cancer drug candidates
  • Multi-step synthesis of pharmaceuticals and bioactive natural products
  • Green chemistry

Experience

    • Sept. 2017 - Present:
      Assistant Professor, NIPER-Ahmedabad (INDIA)
    • Nov. 2013 – Sept. 2017 :
      Post-doctoral Fellow, Department of Chemistry & Biochemistry,North Dakota State University (NDSU), Fargo, USA.
    • April 2011 - Nov. 2013:
      CSIR-Research Associate (CSIR-RA), Department of Medicinal Chemistry, NIPER SAS Nagar (Mohali), India
    • April 2009 - March 2013:
      CSIR-Senior Research Fellow (CSIR-SRF), Department of Medicinal Chemistry, NIPER SAS Nagar (Mohali), India

Honours/Awards/Grants/Consultancies

Awards

  • Best Poster award at 2nd KU-NDSU Joint Symposium on Biotechnology, Nanomaterials and Polymers, Fukushima, Japan, November 2016.
  • 1st Prize of 2013 Eli Lilly and Company Asia Outstanding Thesis Awards.
  • Research Associateship (2011) by Human Resource Development Group, Council of Scientific & Industrial Research (CSIR-HRDG), Government of India.
  • Best Poster award at 14th International Conference (ISCBC-2010) on Chemical Biology for Discovery: Perspectives and Challenges, January 2010, CDRI, Lucknow, India.
  • Senior Research Fellowship (2009) by Human Resource Development Group, Council of Scientific & Industrial Research (CSIR-HRDG), Government of India.
  • Graduate Aptitude Test in Engineering (GATE–2005 category: Pharmaceutical Sciences) with 98.64 percentile

Publications (Research Article or Review Article Max 10)

  • Sandeep R.Vemula, Dinesh Kumar, Gregory R.Cook. (2018) Bismuth-catalyzed synthesis of 2-substituted quinazolinones, Tetrahedron Letters. 59(42), 3801-3805. https://doi.org/10.1016/j.tetlet.2018.09.014
  • Dinesh Kumar, Sandeep Reddy Vemula, Narayanaganesh Balasubramanian, and Gregory R. Cook, "Indium-mediated stereoselective allylation,” Acc. Chem. Res., 2016, 49, 2169–2178; IF 20.00.
  • Dinesh Kumar, Sandeep Reddy Vemula, and Gregory R. Cook, "Merging C–H Bond Functionalization with Amide Alcoholysis: En Route to 2-Aminopyridines,” ACS Catal., 2016, 6, 3531-353; IF 10.6.
  • Dinesh Kumar, Sandeep R. Vemula, and Gregory R. Cook, "Recent advances in catalytic synthesis of α-ketoamides,” ACS Catal., 2016, 6, 4920-4945; IF 10.6.
  • Sandeep Reddy Vemula, Dinesh Kumar, and Gregory R. Cook, "Palladium catalyzed allylic amidation with N-heterocycles via sp3 C-H oxidation,” ACS Catal., 2016, 6, 5295-5301; IF 10.6.
  • Dinesh Kumar, Sandeep Reddy Vemula, and Gregory R. Cook, "Highly chemo- and regioselective allylic substitution with tautomerizable heteroarenes,” Green Chem., 2015, 17, 4300-4306; IF 9.12.
  • Dinesh Kumar, Mukesh Sonawane, Brahmam Pujala, Varun K. Jain, Srikant Bhagat, and Asit K. Chakraborti, "Supported protic acid-catalyzed synthesis of 2,3-disubstituted thiazolidin-4- one: enhancement of the catalytic potential of protic acid by adsorbtion on solid support,” Green Chem., 2013, 15, 2872-2884; IF 9.12.
  • Dinesh Kumar, N. Kommi, Alpesh R. Patel, and Asit K. Chakraborti, "Catalytic procedures for multicomponent synthesis of imidazoles: Selectivity control during the competitive formation of tri- and tetra-substituted imidazoles,” Green Chem., 2012, 14, 2038-2049; IF 9.12.
  • Damodara N. Kommi, Dinesh Kumar, and Asit K. Chakraborti, "All water chemistry for a concise total synthesis of the anti-anginal drug (RS), (R), and (S)-ranolazine,” Green Chem., 2013, 15, 756–767; IF 9.12.
  • Damodara N. Kommi, Pradeep S. Jadhavar, Dinesh Kumar,and Asit K.Chakraborti, "All water” one-pot diverse synthesis of 1,2-disubstituted benzimidazoles: hydrogen bond driven ‘synergistic electrophile-nucleophile dual activation’ by water,” Green Chem., 2013, 15, 798– 810; IF 9.12.
  • Damodara N. Kommi, Dinesh kumar, Rohit Bansal, Rajesh Chebolu, and Asit K. Chakraborti,"All-water chemistry of tandem N-alkylation–reduction–condensation for synthesis of Narylmethyl-2-substituted benzimidazoles,” Green Chem., 2012, 14, 3329-3335; IF 9.12.; (Highlighted in RSC Blog by Mary Badcock, Development Editor, Green Chemistry).
Complete list

Books/Book Chapters/Patents/Peer Review -Abstracts

Book Chapters

  • Pradeep S. Jadhavar, Dinesh Kumar, Priyank Purohit, Bhavin V. Pipaliya, Asim Kumar, Srikant Bhagat, and Asit K. Chakraborti, Chapter Title: "Sustainable approaches towards the synthesis of quinoxalines,” Book Title: Green Chemistry: Synthesis of Bioactive Heterocycles, DOI: 10.1007/978-81-322-1850-0, Online ISBN 978-81-322-1850-0, Publisher- Springer India

Patents

  • Asit K. Chakraborti, Dinesh Kumar, Mukesh Sonawane, and Brahmam Pujala "Processes for synthesis of 2,3-disubstituted-4-thiazolidinone,” Indian Patent Appl. No. 3148/DEL/2011, Date of filing: 08/11/2011, PCT International filing date: 04/11/2011, Date of Publication: 10/05/2013.
  • Asit K. Chakraborti, Dinesh Kumar and Tushar Satav "An improved acid catalyzed one-pot synthesis of 2-styryl quinoline,” Indian Patent Appl. No. 2673/DEL/2011, Date of filing: 15/09/2011, PCT International filing date: 15/09/2011, Date of Publication: 15/03/2013.
  • Asit K. Chakraborti, Dinesh Kumar and Himanshu Sharma "An improved process for one- pot synthesis of 2-styryl-4-(3H)-quinazolinones,” Indian Patent Appl. No. 2443/DEL/2011, Date of filing: 26/08/2011, PCT International filing date: 26/08/2011, Date of Publication: 31/08/2016.
  • Asit K. Chakraborti, Dinesh Kumar Sachin Bindal, and Damodar N. Kommi "An improved process for the synthesis of alkyl ester of carboxylic acid,” Indian Patent Appl. No 2176/DEL/2011, Date of filing: 02/08/2011, PCT International filing date: 02/08/2011, Date of Publication: 11/10/2013.
  • Asit K. Chakraborti,Dinesh Kumar Kapileshwar Seth, and Damodar N. Kommi "A green procedure for synthesis of functionalized compounds,” Indian Patent. Appl. No. 2023/DEL/2011, Date of filing: 18/07/2011, PCT International filing date: 18/07/2011, Date of Publication: 25/01/2013.
  • Asit K. Chakraborti, Alpesh R. Patel, and Dinesh Kumar "An improved catalytic process for esterification of carboxylic acids,” Indian patent. Appl. No. 1046/DEL/2009, Date of filing: 21/05/2009, PCT International filing date: 21/05/2009, Date of Publication: 25/11/2010.
  • Asit K. Chakraborti, Alpesh R. Patel, and Dinesh Kumar "An improved process for esterification using organic carbonates,” Indian Patent. Appl. No. 554/DEL/2009, Date of filing: 23/03/2009, PCT International filing date: 23/03/2009, Date of Publication: 15/10/2010.
  • Asit K. Chakraborti, Dinesh Kumar, Santosh Rudraawar, Sachin Bindal, Himanshu Sharma, and Pradeep Chopra "Improved processes for synthesis of functionalized pyridines,” Indian Patent. Appl. No. 3245/DEL/2012, Date of filing: 18/10/2012, Date of Publication:15/08/2014.
  • Asit K. Chakraborti, Damodar N. Kommi, and Dinesh Kumar"Improved proceses for the synthesis of Lubeluzole,” Indian Patent Appl. No. 1962/DEL/2012, Date of filing: 26/06/2012, Date of Publication: 27/12/2013.

Peer Review Abstract

  • Dinesh Kumar, Sandeep Reddy Vemula, and Gregory R. Cook, "Ruthenium catalyzed site selective olefinic C-H bond functionalization for chemo- and regioselective annulation reaction,” 252nd ACS National Meeting & Exposition, Philadelphia, PA, August 21-25, 2016.
  • Dinesh Kumar, Sandeep Reddy Vemula, and Gregory R. Cook, "Regio and chemoselective allylation of Heterocycles,” 248th ACS National Meeting & Exposition, San Francisco, CA, United States, August 10-14,2014.
  • Sandeep Reddy Vemula, Dinesh Kumar, and Gregory R. Cook, "Investigation and exploration of transition metal catalysis for site selective C-H bond functionalizations,” 251st ACS National Meeting & Exposition, San Diego, CA, USA, March 13-17, 2016.
  • Sandeep Reddy Vemula, Dinesh Kumar, Narayanaganesh Balasubramanian, and Gregory R. Cook, "Main group metal-mediated enantioselective allylation of carbonyl compounds using substoichiometric amounts of metal,” 248th ACS National Meeting & Exposition, San Francisco, CA, USA, August 10-14, 2014.
  • Gregory R. Cook, Sandeep Reddy Vemula, Dinesh Kumar,and Narayanaganesh Balasubramanian, "New paradigm in enantioselective In-mediated allylation,” 248th ACS National Meeting & Exposition, San Francisco, CA, USA, August 10-14, 2014.

Presentations:
National: 00
International: 05
Projects:
Completed: -
Ongoing: 02
PhD:
Completed -
Ongoing: 01
MS Dissertation:
Completed -
Ongoing: 02
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