Dr. Vinod Tiwari, Ph.D

PDF : Johns Hopkins University, Baltimore, MD, USA (2012-2016)

Ph.D : UIPS, Panjab University, Chandigarh, India (2008-2012)

M. Pharm N.D.M.V.P. College of Pharmacy, Nashik, University of Pune, India (2005-2007)

B. Pharm : H.N.B. Garhwal University, Srinagar, Uttarakhand, India (2000-2004)

Dr. Vinod Tiwari, Ph.D

Assistant Professor

Tele: +91 79 66745555

E-mail : vinodtiwari1980@gmail.com

Research Interests & Long-term Career Goals

Dr. Vinod Tiwari, Assistant Professor of Pharmacology & Toxicology at NIPER Ahmedabad, is working in the field of pharmacology & neuroscience from past 11 years. Dr. Tiwari’s research interest is focused on behavioral and molecular neuroscience dedicated to understanding the various neurodegenerative disorders and the signaling pathway involved so that better and safer drug candidates can be developed by targeting the disrupted neuro-machinery. His postdoc research work at Johns Hopkins University, USA was focused on dissecting the key neuronal circuitries involved in pain relief and drug abuse so that better analgesic drugs which are devoid of drug addiction can be developed. He also explored the role of mu-delta heterodimers in peripheral opioid analgesia and tolerance. During his Ph.D at Panjab University, Chandigarh he explored the neuroinflammatory signaling & cell death cascade involved in chronic alcohol induced neuropathy and cognitive deficits which lead to several publications including in PAIN (highest impact research paper in the history of UIPS, Panjab University). Dr. Tiwari contributed immensely in the field of neuroscience with more than 35 research publications, 6 review articles and 3 book chapters in peer reviewed international journals including in Nature Neuroscience (Impact Factor- 15.531), The Journal of Clinical Investigation (Impact Factor- 15.39), Neuron (Impact Factor- 15.982), Anesthesiology (Impact Factor- 5.879), PAIN (Impact Factor- 5.644), International Journal of Neuropsychopharmacology (Impact Factor- 4.874) etc. His research work is rapidly being cited (>950 citations; h–index of 19; cumulative Impact Factor > 250) by researchers all over the world. Dr. Tiwari has delivered several invited research talks and presented his research findings in more than 30 national and international scientific meetings. He is serving as editorial and reviewer board member for many leading journals in the field of pain and neuroscience.

Experience

  • August 2016 - Present:
    Assistant Professor (Pharmacology & Toxicology), NIPER-Ahmedabad, Gujarat, India
  • May 2012 – July 2016:
    Postdoctoral Research Fellow, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
  • May 2009 – May 2012:
    Senior Research Fellow, ICMR, University Institute of Pharmaceutical Sciences, Panjab University, Chandigarh, India.
  • May 2008 – April 2009:
    Senior Research Fellow, CCRAS, University Institute of Pharmaceutical Sciences, Panjab University, Chandigarh, India.
  • Aug 2007 - March 2008:
    Research Associate, Nicholas Piramal Research Center, Nicholas Piramal India Ltd, Mumbai, India.
  • Sept 2005- Aug 2007:
    Junior Research Fellow, AICTE, for pursuing M.Pharm in Pharmacology at N.D.M.V.P. Samaj’s College of Pharmacy, University of Pune, Maharashtra, India

Honors and Awards

  • "Travel award” by International Narcotics Research Conference (INRC) to attend INRC meeting (July 10-14, 2016) at Bath, England, U.K
  • "Travel award” by International Narcotics Research Conference (INRC) to attend INRC meeting (June 15-19, 2015) at Phoenix, Arizona, U.S.A
  • "1st Prize” for poster presentation at 16th Annual ACCM Research Day held at Johns Hopkins University, Baltimore, MD, U.S.A on December 10, 2014
  • "Travel award” by International Narcotics Research Conference (INRC) to attend INRC meeting (July 13 to July 18, 2014) at Montréal, Québec, CANADA
  • "Young Investigator Scientist Award” by International Brain Research Organization for 3 weeks (June 20th-July 13th, 2011) training programme at laboratory of Prof. Patricia Gaspar, School of Neuroscience, Paris, FRANCE
  • Awarded Full travel grant by International Brain Research Organization to attend and present research work at 8th IBRO World Congress of Neuroscience held at Florence, ITALY from July 14-19, 2011
  • Awarded "Best Poster Presentation Award” during UGC-SAP Sponsored National Symposium on"Molecular Pathogenesis of Neurodegenerative Diseases” organized by Department of Biophysics, Panjab University, Chandigarh, India from February 22, 2010
  • Received IBRO International Travel Award to attend 40th Annual Meeting of the Society for Neuroscience, San Diego, California, U.S.A from Nov 13-17th, 2010
  • Received IASP Travel Award to attend 13th World Congress of Pain, Montreal, CANADA from Aug 29-Sept 3rd, 2010
  • Awarded "Best (First) Poster Presentation Award” during Symposium on Natural Products in Health and Disease, Biochemical and Molecular Mechanisms held at Department of Biochemistry, Panjab University, Chandigarh, INDIA from March 5-6th, 2010.
  • Selected for full travel grant from DST to attend 12th International Conference on the Mechanisms and Treatment of Neuropathic Pain held at San Francisco, California, USA from Nov 19 – 21, 2009
  • Received "Most Active Sudent Award” by organizers of IBRO Advanced School of Neuroscience held at Institutes of Brain Science and State Key Laboratory of Medical Neurobiology, Fudan University, Shanghai, CHINA from Oct 26th – Nov 4th, 2009
  • Full travel grant to attend IBRO Advanced School of Neuroscience held at Institutes of Brain Science and State Key Laboratory of Medical Neurobiology, Fudan University, Shanghai, CHINA from Oct 26th – Nov 4th, 2009
  • Full travel grant to attend IBRO-APRC Associate School of Neuroscience held at School of Life Sciences and State Key Laboratory of Pharmaceutical Biotechnology, Nanjing University, Nanjing, CHINA from Aug 18th-22nd, 2009
  • All India Rank 1 in "Professional diploma in Clinical Research” conducted by Catalyst Clinical Services Pvt. Ltd, Delhi, INDIA, Oct 2005
  • 2nd Rank in whole Uttarakhand, India in GATE 2005
  • Won first prize in Chess competition held by the "The Pharmaceutical Society", H.N.B.Garhwal University, Srinagar Garhwal, INDIA, 2002
  • Winner in Inter School Quiz Competition arranged by "St. Paul’s College", Moradabad, INDIA, 1997

Research Publications : Peer-reviewed Original Science Research

  • Tiwari V, He SQ, Liang L, Yang F, Tiwari V, Wang Y, Dong X, Guan Y, Raja SN. Role of mu-delta heterodimers in peripheral opioid analgesia and tolerance in neuropathic rats (under preparation)
  • Tiwari V, Chopra K. Attenuation of oxidative-nitrosative stress mediated inflammatory signaling by resveratrol ameliorates alcoholic neuropathy in rats (under preparation)
  • Tiwari V, Yang F, He SQ, Tiwari V, Shechter R, Zhang C, Shu B, Zhang T, Wang Y, Dong X, Guan Y, Raja SN. Peripheral mu-opioid receptor activation attenuates ongoing neuropathic and inflammatory pain in rats (under preparation)
  • Tiwari V, Sachdeva AK Chopra K. Epigallocatechin-3-gallate prevents alcohol-induced cognitive deficits by attenuating neuroinflammatory signaling (under preparation)
  • Yang F, Xu Q, Shu B, Tiwari V, He SQ, Louis P. Portocarrero V, Dong X, Linderoth B, Raja SN, Wang Y, Guan Y. Activation of cannabinoid CB1 receptor contributes to suppression of spinal nociceptive transmission and inhibition of mechanical hypersensitivity by Aβ-fiber stimulation. PAIN July 2016 (Impact Factor- 5.644) ISSN: 0304-3959
  • Li Z*, Tseng PY*, Tiwari V, Xu Q, Wang Y, Han L, Cui Y, He SQ, Sun S, Zheng Q, Cheng Y, Huang J, Geng Y, Xiao B, Slusher BS, Hopkins CR, Guan Y, Dong X. Allosteric Modulator of Mas-Related G-Protein–Coupled Receptor X1 (MrgprX1) Inhibits Persistent Evoked and Spontaneous Ongoing Pain. The Journal of Clinical Investigation June 2016 (Under revision). (Impact Factor- 15.39) ISSN: 0021-9738. Second Author.
  • Tiwari V, Yang F, He SQ, Shechter R, Zhang C, Shu B, Zhang T,Tiwari V, Wang Y, Dong X, Guan Y, Raja SN. Activation of Peripheral Mu-Opioid Receptors by Dermorphin [D-Arg2, Lys4] (1-4) amide Leads to Modality-preferred Inhibition of Neuropathic Pain. Anesthesiology 2016 Mar;124(3):706-20 (Impact Factor- 5.879) ISSN: 0003-3022
  • Cao J, Wang PK, Tiwari V, Liang L, Lutz BM, Shieh KR, Zang WD, Kaufman AG, Bekker A, Gao XQ, Tao YX. Short-term pre- and post-operative stress prolongs incision-induced pain hypersensitivity without changing basal pain perception. Molecular Pain. 2015 Dec 2;11(1):73. (Impact Factor- 3.654) ISSN: 1744-8069
  • Li Z, He SQ, Tseng PY, Xu Q, Tiwari V, Yang F, Shu B, Zhang T, Tang Z, Raja SN, Wang Y, Dong X, Guan Y. The inhibition of high-voltage-activated calcium current by activation of MrgC11 involves phospholipase C-dependent mechanisms. Neuroscience. 2015 Aug 6;300:393-403. (Impact Factor- 3.357) ISSN: 0306-4522
  • Pang Z, Sakamoto T, Tiwari V, Kim YS, Yang F, Dong X, Güler AD, Guan Y, Caterina MJ. Selective keratinocyte stimulation is sufficient to evoke nociception in mice. PAIN 2015 Apr;156(4):656-65. (Impact Factor- 5.644) ISSN: 0304-3959
Complete list

Review Articles : Peer Reviewed

  • Tiwari V, Tiwari Vinod, He SQ, Zhang T, Raja SN, Dong X, Guan Y. Mas-Related G Protein-Coupled Receptors Offer Potential New Targets for Pain Therapy. Adv Exp Med Biol. 2016;904:87-103. doi: 10.1007/978-94-017-7537-3_7. (co-first author) (Impact Factor- 1.96) ISSN: :0065-2598.
  • Tiwari V*, Guan Y and Raja SN. Modulating the Delicate Glial-Neuronal Interactions in Neuropathic Pain: Promises and Potential Caveats. Neuroscience & Biobehavioral Reviews 2014 Sep; 45C:19-27. (Impact Factor- 10.284). ISSN: 0149-7634.*Corresponding author
  • Chopra K, Tiwari V. Alcoholic Neuropathy: Possible Mechanisms and Future Treatment Possibilities. British Journal of Clinical Pharmacology 2012 Mar; 73(3) : 348-62 (Impact Factor- 3.063) ISSN: 1365-2125.
  • Chopra K, Tiwari V. Fetal Alcohol Spectrum Disorders: An Overview of Diverse Mechanisms Involved. Pharmacos 2010; 37:37-43.
  • Chopra K, Kuhad A, Tiwari V. Rheumatoid Arthritis: A Pathobiological Perspective. Pharmacos 2009; 36:26-31.

Book Chapters:

  • Tiwari V, Chopra K. Neuropathobiology of Alcohol-induced Cognitive Deficits, The Neuropathology of Drug Addictions and Substance Misuse; pp.618-626, Preedy V.R. (Eds.), DOI: 10.1016/B978-0-12-800213-1.00057-2
  • Chopra K, Tiwari V, 2012. Tocotrienol and Cognitive Dysfunction Induced by Alcohol, in; Watson R.R, Preedy V.R. (Eds.), Alcohol, Nutrition, and Health Consequences. Humana Press, Springer pp- 181-202.
  • Chopra K, Kuhad A,Tiwari V, 2011. Vitamin E and Neuroinflammtion, in: Hermann W, Obeid\ R (Eds.), Vitamins in the prevention of human diseases. De Gruyter, New York, pp- 482-503.

Abstracts Published:

  • Kuhad A, Bishnoi M, Tiwari V, Chopra K. Tocotrienol attenuates diabetes-associated cognitive deficits in rats. Alzheimer's and Dementia, 2009; 5(4,1),P44 (Impact Factor- 5.902) ISSN: I1552-5260. AAIC Alzheimer's Neuroscience Conference, July 11 - 16, 2009; Vienna, Austria.
  • Tiwari V, Kuhad A, Arora V, Chopra K. Neuroprotective effect of epigallocatechin-3-gallate against chronic alcohol induced cognitive deficits in rats: Possible role of oxidative stress and cytokine signaling. Alzheimer's and Dementia July 2010; 6(4), 1:S580. (Impact Factor- 5.902) ISSN: I1552-5260. AAIC Alzheimer's Neuroscience Conference, July 10 to 15, 2010, Honolulu, Hawaii
  • Tiwari V, Kuhad A, Chopra K. Downregulation Of oxido-inflammatory cascade In alcoholic neuropathic pain by epigallocatechin-3-gallate. European Journal of Pain Supplements, Volume 4, Issue 1, April 2010, Page 61. (Impact Factor- 3.819) ISSN: 1090-3801

Membership of Scientific Committees:

  • Association of Basic Medical Scientists (ABMS), PGIMER, Chandigarh, India
  • Society for Neuroscience (SfN), 1121 14th Street, NW Suite 1010 Washington, DC 20005, USA
  • International Association for the study of Pain (IASP), 111 Queen Anne Ave N, Suite 501Seattle, WA 98109-4955 USA
  • Indian Pharmacological Society (IPS), Hyderabad, India
  • International Brain Research Organization (IBRO), 255 rue Saint-Honoré, 75001 Paris, France
Presentations:
National : 10
International: 22
Projects : -
Ph. D Thesis*
Completed 0
Ongoing 01
MS/M. Pharm Dissertation:
Completed: 0
Ongoing: 04
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