Dr. Vinod Tiwari, Ph.D

Visiting Professor : Department of Anesthesiology, Johns Hopkins University, Baltimore, MD, USA (2017-2018)
PDF : Johns Hopkins University School of Medicine, Baltimore, MD, USA (2012-2016)

Ph.D : UIPS, Panjab University, Chandigarh, India (2008-2012)

Dr. Vinod Tiwari, Ph.D

Assistant Professor

Tele: +91 79 66745555

E-mail : vinodtiwari1980@gmail.com,tiwari.vinod@niperahm.ac.in

Research Interest

Dr. Vinod Tiwari, Assistant Professor of Pharmacology & Toxicology at NIPER Ahmedabad, is working in the field of pharmacology & neuroscience from past 12 years. Dr. Tiwari’s research interest is focused on behavioral and molecular neuroscience dedicated to understanding the various neurodegenerative disorders and the signaling pathway involved so that better and safer drug candidates can be developed by targeting the disrupted neuro-machinery. His lab is working on differentiating the key neuronal circuitries involved in pain relief and drug addiction so that better analgesic drugs devoid of drug addiction can be developed. His other areas of research interest includes diabetes and microvascular complications. Dr. Tiwari contributed immensely in the field of neuroscience with more than 38 research publications, 6 review articles and 3 book chapters in peer reviewed international journals including in PNAS, Nature Neuroscience, The Journal of Clinical Investigation, Neuron, Anesthesiology, International Journal of Neuropsychopharmacology etc. His research work is rapidly being cited (>1235 citations; h–index of 21; cumulative Impact Factor > 200) by researchers all over the world. He is currently working on different collaborative projects at Johns Hopkins University, Harvard Medical School and Memorial Sloan-Kettering Cancer Center at USA.

Experience

  • August 2016 - Present:
    Assistant Professor (Pharmacology & Toxicology), NIPER-Ahmedabad, Gandhinagar, Gujarat, India
  • May 2012 – July 2016:
    Postdoctoral Research Fellow, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
  • May 2009 – May 2012:
    Senior Research Fellow, ICMR, University Institute of Pharmaceutical Sciences, Panjab University, Chandigarh, India.
  • May 2008 – April 2009:
    Senior Research Fellow, CCRAS, New Delhi University Institute of Pharmaceutical Sciences, Panjab University, Chandigarh, India.
  • Aug 2007 - March 2008:
    Research Scientist, Nicholas Piramal Research Center, Nicholas Piramal India Ltd, Mumbai, India.
  • Sept 2005- Aug 2007:
    Junior Research Fellow, AICTE, New Delhi for pursuing M.Pharm in Pharmacology at N.D.M.V.P. Samaj’s College of Pharmacy, University of Pune, Maharashtra, India

Honours/Awards/Grants/Consultancies

Awards

  • "Travel award” by International Narcotics Research Conference (INRC) to attend INRC meeting (July 10-14, 2016) at Bath, England, U.K
  • "Travel award” by International Narcotics Research Conference (INRC) to attend INRC meeting (June 15-19, 2015) at Phoenix, Arizona, U.S.A
  • "1st Prize” for poster presentation at 16th Annual ACCM Research Day held at Johns Hopkins University, Baltimore, MD, U.S.A on December 10, 2014
  • "Travel award” by International Narcotics Research Conference (INRC) to attend INRC meeting (July 13 to July 18, 2014) at Montréal, Québec, CANADA
  • "Young Investigator Scientist Award” by International Brain Research Organization for 3 weeks (June 20th-July 13th, 2011) training programme at laboratory of Prof. Patricia Gaspar, School of Neuroscience, Paris, FRANCE
  • Awarded Full travel grant by International Brain Research Organization to attend and present research work at 8th IBRO World Congress of Neuroscience held at Florence, ITALY from July 14-19, 2011
  • Awarded "Best Poster Presentation Award” during UGC-SAP Sponsored National Symposium on"Molecular Pathogenesis of Neurodegenerative Diseases” organized by Department of Biophysics, Panjab University, Chandigarh, India from February 22, 2010
  • Received IBRO International Travel Award to attend 40th Annual Meeting of the Society for Neuroscience, San Diego, California, U.S.A from Nov 13-17th, 2010
  • Received IASP Travel Award to attend 13th World Congress of Pain, Montreal, CANADA from Aug 29-Sept 3rd, 2010
  • Awarded "Best (First) Poster Presentation Award” during Symposium on Natural Products in Health and Disease, Biochemical and Molecular Mechanisms held at Department of Biochemistry, Panjab University, Chandigarh, INDIA from March 5-6th, 2010.
  • Selected for full travel grant from DST to attend 12th International Conference on the Mechanisms and Treatment of Neuropathic Pain held at San Francisco, California, USA from Nov 19 – 21, 2009
  • Received "Most Active Sudent Award” by organizers of IBRO Advanced School of Neuroscience held at Institutes of Brain Science and State Key Laboratory of Medical Neurobiology, Fudan University, Shanghai, CHINA from Oct 26th – Nov 4th, 2009
  • Full travel grant to attend IBRO Advanced School of Neuroscience held at Institutes of Brain Science and State Key Laboratory of Medical Neurobiology, Fudan University, Shanghai, CHINA from Oct 26th – Nov 4th, 2009
  • Full travel grant to attend IBRO-APRC Associate School of Neuroscience held at School of Life Sciences and State Key Laboratory of Pharmaceutical Biotechnology, Nanjing University, Nanjing, CHINA from Aug 18th-22nd, 2009
  • All India Rank 1 in "Professional diploma in Clinical Research” conducted by Catalyst Clinical Services Pvt. Ltd, Delhi, INDIA, Oct 2005
  • 2nd Rank in whole Uttarakhand, India in GATE 2005
  • Won first prize in Chess competition held by the "The Pharmaceutical Society", H.N.B.Garhwal University, Srinagar Garhwal, INDIA, 2002
  • Winner in Inter School Quiz Competition arranged by "St. Paul’s College", Moradabad, INDIA, 1997

Grants

  • DST Early Career Research Award (June 2017-May 2020)Grant title, :Dissecting Brain Reward Circuitry and CNS Comorbidities in Chronic Neuropathic Pain.Role : Principle InvestigatorBlaustein Pain Research Grant (Jan 2016-Dec 2016)Grant title :Turning the pain relief-reward wheel to produce negative reinforcement with peripherally acting opioids and cannabinoids.Role :Co-investigator
  • Indian Council of Medical Research (June 2009-May2012)Grant title :To investigate the potential of polyphenolic anti-inflammatory agents in rheumatoid arthritis.Role :Senior Research Fellow

Publications

  • Tiwari V, Yang F, He SQ, Tiwari V, Shechter R, Zhang C, Shu B, Zhang T, Wang Y, Dong X, Guan Y, Raja SN. Peripheral mu-opioid receptor activation attenuates ongoing neuropathic and inflammatory pain in ratsAnesthesiology 2017 (Under revision) (Impact Factor- 5.879) ISSN: 0003-3022
  • He SQ, Xu Q, Tiwari V, Yang F, Anderson M, Chen Z, Grenald S, Raja SN, Dong X, Guan Y*. MrgC11 and μ-opioid receptor Oligomerization and Interaction enhances morphine analgesia.The Journal of Clinical Investigation 2017 (Under Revision).(Impact Factor- 13.215)ISSN: 0021-9738
  • Li Z, Tseng PY, Tiwari V, Xu Q, He SQ, Wang Y, Zheng Q, Han L, Wu Z, Blobaum AL, Cui Y, Tiwari V, Sun S, Cheng Y, Huang-Lionnet JH, Geng Y, Xiao B, Peng J, Hopkins C, Raja SN, Guan Y*, Dong X*. Targeting human Mas-related G protein-coupled receptor X1 to inhibit persistent pain. Proc Natl Acad Sci U S A. 2017 Mar 7;114(10):E1996-E2005. (Impact Factor- 9.423) ISSN: 1091-6490. First co-author.
  • Yang F, Xu Q, Shu B, Tiwari V, He SQ, Louis P. Portocarrero V, Dong X, Linderoth B, Raja SN, Wang Y, Guan Y. Activation of cannabinoid CB1 receptor contributes to suppression of spinal nociceptive transmission and inhibition of mechanical hypersensitivity by Aβ-fiber stimulation. PAIN 2016 Nov;157(11):2582-2593. (Impact Factor- 5.644) ISSN: 0304-3959
  • Tiwari V, Yang F, He SQ, Shechter R, Zhang C, Shu B, Zhang T,Tiwari V, Wang Y, Dong X, Guan Y, Raja SN. Activation of Peripheral Mu-Opioid Receptors by Dermorphin [D-Arg2, Lys4] (1-4) amide Leads to Modality-preferred Inhibition of Neuropathic Pain. Anesthesiology 2016Mar;124(3):706-20(Impact Factor- 5.879)ISSN: 0003-3022
  • Cao J, Wang PK, Tiwari V, Liang L, Lutz BM, Shieh KR, Zang WD, Kaufman AG, Bekker A, Gao XQ, Tao YX. Short-term pre- and post-operative stress prolongs incision-induced pain hypersensitivity without changing basal pain perception. Molecular Pain. 2015 Dec 2;11(1):73.(Impact Factor- 3.654) ISSN: 1744-8069
  • Li Z, He SQ, Tseng PY, Xu Q, Tiwari V, Yang F, Shu B, Zhang T, Tang Z, Raja SN, Wang Y, Dong X, Guan Y. The inhibition of high-voltage-activated calcium current by activation of MrgC11 involves phospholipase C-dependent mechanisms. Neuroscience. 2015 Aug 6;300:393-403.(Impact Factor- 3.357) ISSN: 0306-4522
  • Pang Z, Sakamoto T, Tiwari V, Kim YS, Yang F, Dong X, Güler AD, Guan Y, Caterina MJ. Selective keratinocyte stimulation is sufficient to evoke nociception in mice.PAIN 2015Apr;156(4):656-65.(Impact Factor- 5.644) ISSN: 0304-3959
  • Weng HJ, Patel KN, Jeske NA, Bierbower SM, Zou W, Tiwari V, Zheng Q, Tang Z, Mo GC, Wang Y, Geng Y, Zhang J, Guan Y, Akopian AN, Dong X*. Tmem100 is a regulator of TRPA1-TRPV1 complex and contributes to persistent pain.Neuron. 2015Feb 18;85(4):833-46.(Impact Factor- 15.982)ISSN: 0896-6273
  • Sdrulla AD, Xu Q, He SQ, Tiwari V, Yang F, Zhang C, Shu B, Shechter R, Raja SN, Wang Y, Dong X, Guan Y*. Electrical stimulation of low-threshold afferent fibers induces a prolonged synaptic depression in lamina II dorsal horn neurons to high-threshold afferent inputs in mice. Pain. 2015 Jun;156(6):1008-17. (Impact Factor- 3.067) ISSN: 1532-2149
Complete list

Book/Book Chapters/Patents/Peer Review -Abstract

Book Chapters

  • Tiwari V, Chopra K. Neuropathobiology of Alcohol-induced Cognitive Deficits, The Neuropathology of Drug Addictions and Substance Misuse; pp.618-626, Preedy V.R. (Eds.), DOI: 10.1016/B978-0-12-800213-1.00057-2
  • Chopra K, Tiwari V, 2012. Tocotrienol and Cognitive Dysfunction Induced by Alcohol, in; Watson R.R, Preedy V.R. (Eds.), Alcohol, Nutrition, and Health Consequences. Humana Press, Springer pp- 181-202.
  • Chopra K, Kuhad A,Tiwari V, 2011. Vitamin E and Neuroinflammtion, in: Hermann W, Obeid\ R (Eds.), Vitamins in the prevention of human diseases. De Gruyter, New York, pp- 482-503.

Peer Review -Abstracts

  • Kuhad A, Bishnoi M, Tiwari V, Chopra K. Tocotrienol attenuates diabetes-associated cognitive deficits in rats. Alzheimer's and Dementia, 2009; 5(4,1),P44 (Impact Factor- 5.902) ISSN: I1552-5260. AAIC Alzheimer's Neuroscience Conference, July 11 - 16, 2009; Vienna, Austria.
  • Tiwari V,Kuhad A, Arora V, Chopra K. Neuroprotective effect of epigallocatechin-3-gallate against chronic alcohol induced cognitive deficits in rats: Possible role of oxidative stress and cytokine signaling. Alzheimer's and Dementia July 2010; 6(4), 1:S580. (Impact Factor- 5.902) ISSN: I1552-5260. AAIC Alzheimer's Neuroscience Conference, July 10 to 15, 2010, Honolulu, Hawaii
  • Tiwari V,Kuhad A, Chopra K. Downregulation Of oxido-inflammatory cascade In alcoholic neuropathic pain by epigallocatechin-3-gallate. European Journal of Pain Supplements, Volume 4, Issue 1, April 2010, Page 61. (Impact Factor- 3.819) ISSN: 1090-3801

Presentations:

National : 10
International: 22
Projects
Completed 02
Ongoing 01
Ph. D
Completed 0
Ongoing 03
MS Dissertation
Completed: 04
Ongoing: 08
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