• Our Group is interested in blending the strategies of synthetic organic chemistry along with the medicinal aspects of natural products for the development of New Chemical Entities (NCEs) against Cancer and Neurodegenerative disorders.
• Total Synthesis and semi synthesis of bioactive Natural products and its structural modification via C-H functionalization and C-C coupling reactions.
• Design and construction of fluorine containing scaffolds of pharmaceutical importance via C-H Bond activation. Incorporation of Fluorine into the bioactive natural product scaffolds and its biological evaluation.
• Peripheral functionalization of porphyrin ring systems for photodynamic therapy.

• December 2019 - Present:
  Assistant Professor, NIPER-Ahmedabad (INDIA)
• January 2017 - December 2019:
  Assistant Professor (DST-INSPIRE Faculty), NIPER-Ahmedabad (INDIA)
• September 2012 – December 2016:
  Research Professor (Postdoctoral Research): School of Pharmacy, Sungkyunkwan University (South Korea)
• June 2012 - August 2012 (3 Months):
  Postdoctoral Research, School of Pharmacy, Kyunghee University (South Korea)
• July 2011 - June 2012 (1 Year):
  Postdoctoral Research: Department of Chemistry, University of Ulsan (South Korea)

Awards

• DST-INSPIRE FACULTY (2016): Project Title: Design and Construction of Fluorine Containing Scaffolds via C-H Bond Activation
• Awarded Fund from National Research Foundation (NRF), South Korea for Basic Research for 3 years, Project title; C-H activation for the formation of new carbon-carbon and carbon-nitrogen bond formation, Award No.: 2013058800.
• KRF (Korea Research Fellowship) fellowship (foreign PhD holder) in 2015 for 5 years funded by Ministry of Science, ICT and Future Planning, South Korea.
• Senior Research Fellowship (SRF), Council of Scientific and Industrial Research (CSIR), India, Jan 2010- April 2011
• Junior Research Fellowship (JRF), Council of Scientific and Industrial Research (CSIR), India, Jan 2008-Dec 2009
• University Grant Commission National Eligibility Test (UGC-NET), June 2007

Grant

• National Research Foundation (NRF) Grant, South Korea for Basic Research for 3 years, Project title; CH activation for the formation of new carbon-carbon and carbon-nitrogen bond formation, Award No.: 20130588002013-2015

• Prasanna Anjaneyulu Yakkala, Deepesh Giri, Bharatkumar Chaudhary and Prashant Auti,Satyasheel Sharma. (2019) Regioselective C–H Alkylation and Alkenylation at C5 Position of 2-Amino-1,4-Naphthoquinones with Maleimides Under Rh(III) Catalysis, Organic Chemistry Frontiers. Doi. 10.1039/C9QO00538B (Advance Article)(I.F 5.455)
• Bharatkumar Chaudhary , Prashant Auti, Suchita Dattatray Shinde, Prasanna Anjaneyulu Yakkala, Deepesh Giri, andSatyasheel Sharma. (2019) Rh(III)-Catalyzed [3 + 2] Annulation via C–H Activation: Direct Access to Trifluoromethyl-Substituted Indenamines and Aminoindanes, organic letters. 21 (8), 2763–2767. DOI: 1021/acs.orglett.9b00720 (I.F 6.492)
• Bharatkumar Chaudhary, Monika Diwaker and Satyasheel Sharma.(2018) Regioselective indole C2-alkylation using β-CF3-substituted enones under redox neutral Rh(III) catalysis, Organic Chemistry Frontiers. 21 (18),3133-3137 .1039/C8QO00932E.
• Khemchand Surana, Bharatkumar Chaudhary , Monika Diwaker and Satyasheel Sharma. (2018) Benzophenone: A Ubiquitous Scaffold in Medicinal Chemistry, MedChemComm.11(9), 1803-1817. 10.1039/C8MD00300A.
• Recent Advances in Catalytic C (sp2)–H Allylation Reactions
  Neeraj Kumar Mishra, Satyasheel Sharma, Jihye Park, Sangil Han, In Su Kim, ACS Catalysis,2017, 7, 2821-2847
• Rhodium-Catalyzed [3 + 2] Annulation of Cyclic N‑Acyl Ketimines with Activated Olefins: Anticancer Activity of Spiroisoindolinones
  Satyasheel Sharma, Yongguk Oh, Neeraj Kumar Mishra, Umasankar De, Hyeim Jo, Richa Sachan, Hyung Sik Kim, Young Hoon Jung, In Su Kim, J. Org. Chem., 2017, 82 (7), pp 3359–3367 (Impact Factor = 4.785) SELECTED as Featured Article.
• Cross-Coupling of Acrylamides and Maleimides under Rhodium Catalysis: Controlled Olefin Migration
  Satyasheel Sharma, Sang Hoon Han, Yongguk Oh, Neeraj Kumar Mishra, Suk Hun Lee, Joa Sub Oh, In Su Kim, Org. Lett. 2016, 18, 2568−2571.
• Mild and Site-Selective Allylation of Enol Carbamates with Allylic Carbonates under Rhodium Catalysis
  Satyasheel Sharma, Sang Hoon Han, Yongguk Oh, Neeraj Kumar Mishra, Sangil Han, Jong Hwan Kwak, Seok-Yong Lee, Young Hoon Jung, In Su Kim, J. Org. Chem. 2016, 81, 2243−2251.
• Rh(III)-catalyzed direct coupling of azobenzenes with α‑diazoesters: facile synthesis of cinnolin-3(2H)-ones
  Satyasheel Sharma, Sang Hoon Han, Sangil Han, Wontae Ji, Jongchan Oh, Seok-Yong Lee, Joa Sub Oh, Young Hoon Jung, In Su Kim, Org. Lett., 2015, 17(11), 2852-2855.
• Rh-catalyzed oxidative C–C bond formation and C–N bond cleavage: direct access to C2-olefinated free (NH)-indoles and pyrroles
  Satyasheel Sharma, Sangil Han, Mirim Kim, Neeraj Kumar Mishra, Jihye Park, Youngmi Shin, Jimin Ha, Jong Hwan Kwak, Young Hoon Jung, In Su Kim, Org. Biomol. Chem., 2014, 12, 1703–1706.
• Pd(II)-catalyzed direct C–H acylation of N-Boc hydrazones with aldehydes: one-pot synthesis of 1,2-diacylbenzenes
  Satyasheel Sharma, Aejin Kim, Jihye Park, Mirim Kim, Jong Hwan Kwak, Young Hoon Jung, Jung Su Park, and In Su Kim, Org. Biomol. Chem., 2013, 11, 7869–7876.
• Palladium-catalyzed decarboxylative acylation of O-phenyl carbamates with α-oxocarboxylic acids at room temperature
  Satyasheel Sharma, Aejin Kim, Eonjeong Park, Jihye Park, Minyoung Kim, Jong Hwan Kwak, Sang Hwi Lee, Young Hoon Jung, In Su Kim, Advanced Synthesis & Catalysis, 2013,355, 4, 667–672.
• Palladium-catalyzed oxidative acylation of N-benzyltriflamides with aldehydes via C–H bond activation
  Satyasheel Sharma, Jihye Park, Eonjeong Park, Aejin Kim, Minyoung Kim, Jong Hwan Kwak, Young Hoon Jung, In Su Kim, Advanced Synthesis & Catalysis, 2013, 355, 2-3, 332–336.
• Tandem Rh(III)-catalyzed oxidative acylation of secondary benzamides with aldehydes and intramolecular cyclization: the direct synthesis of 3-hydroxyisoindolin-1-ones
  Satyasheel Sharma, Eonjeong Park, Jihye Park, In Su Kim, Org. Lett., 2012, 14, 3, 906-909.

Peer Review Abstract

• "Rh(III)-Catalyzed Allylation of Enol Carbamates with Allylic Carbonates" in 3rd International Symposium on C–H activation (3rd ISCHA) at Université de Montréal, Canada, from 30/05/2016 to 03/06/2014.
• "An Efficient Synthesis of Cinnolin-3(2H)-ones via Rh catalyzed C-H Bond Activation of Azobenzenes" in IKCOC-13 at Kyoto, Japan from 09/11/2015 to 13/11/2015.
• "Catalytic C−H Bonds Functionalization: Facile Approach to Bioactive Heterocylic Moieties" in 10th AFMC International Medical Chemistry Symposium AIMECS15 at Jeju Island, South Korea from 18/10/2015 to 21/10/ 2015
• "Rh(III)-Catalyzed mild and selective access to indolic scaffolds with an allylic alcohol moiety" in 16th Tetrahedron Symposium at Grand Hyatt Berlin, Germany from 16/06/2015 to 19/06/2015.
• "Synthesis Ru-catalyzed C-H bond allylation of carboxamides with allyl carbonates" in 8th Singapore International Chemistry Conference (SICC8) at National University of Singapore, Singapore, from 14/12/2014 to 17/12/2014.
• "Synthesis and functionalization of heterocyclic compounds via Rh-catalyzed C–H bond activation" in 2nd International Symposium on C–H activation (2nd ISCHA) at University of Rennes, France, from 30/06/2014 to 03/07/2014.