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Dr. Amit Shard, Ph.D.

Associate Professor , Department of Medicinal Chemistry

Research Interest

Research Area

  • PKM2-Targeted Drug Discovery & Medicinal Chemistry – Rational design and development of small-molecule PKM2 modulators for cancer and pain therapeutics.
  • Cancer Therapeutics & Chemical Biology – Discovery of mechanism-driven small molecules targeting cancer metabolism and tumor progression.
  • Pain & Inflammation Drug Discovery – Development of novel small-molecule therapeutics for inflammatory and neuropathic pain.
  • Bioorganometallic Chemistry – Design and biological evaluation of organometallic compounds as therapeutic agents and chemical probes.
  • Translational Drug Discovery – Target validation, lead optimization, and preclinical evaluation of drug candidates from molecular mechanism to in vivo efficacy.

Experience

  • 2024 - Present
    Associate Professor

    NIPER-Ahmedabad, Palaj Gandhinagar

  • June 2014-2024
    Assistant Professor

    NIPER-Ahmedabad, Palaj Gandhinagar

  • April, 2011-April 2014
    Senior Research Fellowship

    by Council of Scientific and Industrial Research, New Delhi

  • July 2008-March 2011
    Project Assistantship

    CSIR-IHBT, Palampur, H.P

Grants

  1. Indian Council of Medical Research (ICMR)-funded small extramural grant
    (No: 5/4/8-29/CD/AS/2022-NCD-II)
  2. Gujarat State Biotechnology Mission (GSBTM), Department of Science & Technology,
    Government of Gujarat-funded extramural grant
    (GSBTM/JD(R&D)/618/21-22/ooooJG-5)
  3. Science and Engineering Research Board (SERB)-funded Karyashala Program grant.
  4. Department of Biotechnology (DBT)-funded extramural grant
    (No. DBT project no. BT/PR47609/CMD/150/19/2023)
  5. Gujarat State Biotechnology Mission (GSBTM), Department of Science & Technology,
    Government of Gujarat-funded extramural grant
    (No. 2026-27_5)

Patents

  1. Ferrocene-based pyrazolopyrimidine compounds and their uses thereof (2022).
    Granted Indian Patent No: 568053
  2. A series of imidazopyri(mi)dine-based sulfonamide compounds and uses thereof (2024).
    Granted Indian Patent No: 512457
  3. Polyheterocyclic imidazole derivatives, chemical entities thereof, and their pharmaceutical applications (2026).
    Indian Patent Filing No: 202621080184
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