Honours

Grants Completed
1.DST-RSF, Indo-Russia International Collaboration Research Grant, Unraveling the molecular mechanism of lncRNAs involvement in Glioblastoma (72 lakhs, July 2019-Jan 2023)
2.Early Career Research Award – DST SERB, Understanding Wnt Pathway and LncRNAs interaction for the identification of novel therapeutic targets in triple-negative breast cancers (48 lakhs, March 2019-June 2022)
3.Indian Council of Medical Research (ICMR), Identifying the role of P53 regulated long non- coding RNAs (LncRNAs) by Crispr/Cas9 in ovarian cancer (50 lakhs, August 2019- August 2022)

Grants Ongoing
1.Indian Council of Medical Research (ICMR), Investigating of the role of LncRNA PANDAR in the progression and metastasis of ovarian cancer (42 lakhs, January 2022-December 2024)
2.Indian Council of Medical Research (ICMR), Senior Research Fellowship 2022- Samarth Kansara (Student), Elucidating the role of Wnt regulated IncRNA Linc00645 in the pathogenesis of Triple-Negative Breast Cancer as a key therapeutic target. (14 Lakhs, June 2022- June 2024), Amity University Haryana
3.Indian Council of Medical Research (ICMR), Senior Research Fellowship 2022- Abhisesh Kumar Badal (Student), Identification of p53 mediated LINC01021 lncRNA and use as a potential therapeutic (Biomarker)/diagnostic tool in Ovarian cancer. (14 lakhs, March 2022- March 2024), Amity University Haryana

Awards:
1.Indian Association for Cancer Research, Ram Nath Hiralal Jaju Award for best oral presentation by Mid-level Scientist in 41stAnnual Conference of the IACR2022 held on 2nd to 5th March 2022.
2.Best poster award for HUGO gene Nomenclature in HGM 2008, HUGO’s 13th Human Genome Meeting, Hyderabad, India, 27 – 30 Sept 2008.
3.Senior Research fellowship, 2009 from Council of Scientific and Industrial Research (CSIR), Govt. of India.
4.Travel Grant from Department of Science and Technology (DST), Govt. of India to attend Keystone Conference “RNA Silencing: Mechanism, Biology and Application”, Colorado, USA, 14th – 19th January 2010
5.Travel Grant from Council of Scientific and Industrial Research, Govt. of India (CSIR) to attend Keystone Conference “RNA Silencing: Mechanism, Biology and Application”, Colorado, USA, 14th – 19th January 2010

Member of the Editorial Board (Journals)
• Frontiers in Molecular Bioscience
• Plos One
• BMC Molecular and Cell Biology
• BMC Genomics

Professional Member
• Member of the Royal Society of Biology, London
• Life Member of Biotech Research Society of India

Publications

Research Publications

1.Kansara S, Singh A, Badal AK, Rani R, Baligar P, Garg M, Pandey AK. The emerging regulatory roles of non-coding RNAs associated with glucose metabolism in breast cancer. Semin Cancer Biol. 2023 Oct; 95:1-12. (IF: 14)
2.Kovalenko TF, Yadav B, Anufrieva KS, Larionova TD, Aksinina TE, Latyshev YA, Bastola S, Shakhparonov MI, Pandey AK, Pavlyukov MS. PTEN regulates expression of its pseudogene in glioblastoma cells in DNA methylation-dependent manner. Biochimie. 2023 Aug 22:S0300-9084(23)00201-8 (IF-3.6)
3.Bansal Isha, Pandey Amit Kumar, Ruwali Munindra. Small-molecule inhibitors of kinases in breast cancer therapy: recent advances, opportunities, and challenges. Frontiers in Pharmacology. 2023, Aug; 14 (IF- 5.6)
4.Jain CK, Srivastava P, Pandey AK, Singh N, Kumar RS. miRNA therapeutics in precision oncology: a natural premium to nurture. Explor Target Antitumor Ther. 2022;3(4):511- 532.
5.Varun Rawat, Arkadi Vigalok, Anshu Kumar Sinha, Garima Sachdeva, Chandra Mohan Srivastava, Gyandshwar K. Rao*, Arun Kumar, Mandeep Singh, Komal Rathi, Ved Prakash Verma, Bhupender Yadav, Amit Kumar Pandey, Monika Vats. Synthesis of a Zirconium Complex of an N,O-type p-tert- Butylcalix[4]arene and Its Application in Some Multicomponent Reactions. ACS Omega. 2022, 7, 32, 28471- 28480. (IF: 4.1)
6.Kovalenko TF, Yadav B, Anufrieva KS, Rubtsov YP, Zatsepin TS, Shcherbinina EY, Solyus EM, Staroverov DB, Larionova TD, Latyshev YA, Shakhparonov MI, Pandey AK, Pavlyukov MS. Functions of long non- coding RNA ROR in patient-derived glioblastoma cells. Biochimie. 2022 May 30; 200:131-139. (IF: 4.37)
7.Anuradha Kirtonia, Amit Kumar Pandey, Balaji Ramachandran, Durga Prasad Mishra, David W Dawson, Gautam Sethi, Trivadi S Ganesan, H Phillip Koeffler, Manoj Garg. Overexpression of Laminin-5 Gamma-2 promotes tumorigenesis of pancreatic ductal adenocarcinoma through EGFR/ERK1/2/AKT/mTOR cascade. Cell Mol Life Sci. 2022 Jun 14;79(7):362 (IF: 9.2)
8.Kirtonia A, Ashrafizadeh M, Zarrabi A, Hushmandi K, Zabolian A, Bejandi AK, Rani R, Pandey AK, Baligar P, Kumar V, Das BC, Garg M. Long noncoding RNAs: A novel insight in the leukemogenesis and drug resistance in acute myeloid leukemia. J Cell Physiol. 2022 Jan;237(1):450-465 (IF: 6.38)
9.Ayushi Sharma, Samarth Kansara, Mehul Mahajan, Bhupender Yadav, Manoj Garg, Amit Kumar Pandey, Long non-coding RNAs orchestrate various molecular and cellular processes by modulating epithelial- mesenchymal transition in head and neck squamous cell carcinoma, 2021, 166240, ISSN 0925-4439, Biochim Biophys Acta Mol Basis Dis. 2021 Nov 1;1867(11):166240 (IF: 5.18.)
10.Pandya G, Kirtonia A, Singh A, Goel A, Mohan CD, Rangappa KS, Pandey AK, Kapoor S, Tandon S, Sethi G, Garg M. A comprehensive review of the multifaceted role of the microbiota in human pancreatic carcinoma. Semin Cancer Biol. 2021 May 26: S1044-579X (21)00157-7. (IF-15.7)
11.Yadav B, Pal S, Rubstov Y, Goel A, Garg M, Pavlyukov M, Pandey AK. Long non-coding RNAs Associated with Glioblastoma: From Transcriptional Noise to Novel Regulators with a Promising Role in Therapeutics. Mol Ther Nucleic Acids. 2021 Apr 2; 24:728-742. (IF-8.88)
12.Pandya, A. Kirtonia, G. Sethi, A.K. Pandey, M. Garg, The implication of long non-coding RNAs in the diagnosis, pathogenesis and drug resistance of pancreatic ductal adenocarcinoma and their possible therapeutic potential, Biochim Biophys Acta Rev Cancer. 2020 Dec;1874(2):188423. (IF-10.68)
13.Sin ZW, Bhardwaj V, Pandey AK, Garg M. A brief overview of antitumoral actions of bruceine D. Explor Target Antitumor Ther. 2020;1(4):200-217.
14.Kirtonia, G. Pandya, G. Sethi, A.K. Pandey, B.C. Das, M. Garg, A comprehensive review of genetic alterations and molecular targeted therapies for the implementation of personalized medicine in acute myeloid leukemia, J Mol Med (Berl). 2020 Aug;98(8):1069-1091. (IF-4.59)
15.S. Kansara, V. Pandey, P.E. Lobie, G. Sethi, M. Garg, A.K. Pandey, Mechanistic Involvement of Long Non- Coding RNAs in Oncotherapeutics Resistance in Triple-Negative Breast Cancer, Cells. 2020 Jun 21;9(6):1511. (IF-6.6)
16.Kirtonia, K. Gala, S.G. Fernandes, G. Pandya, A.K. Pandey, G. Sethi, E. Khattar, M. Garg, Repurposing of drugs: An attractive pharmacological strategy for cancer therapeutics, Semin Cancer Biol. 2021 Jan;68:258- 278 (IF- 15.7)
17.S. Pal, M. Garg, A.K. Pandey, Deciphering the Mounting Complexity of the p53 Regulatory Network in Correlation to Long Non-Coding RNAs (lncRNAs) in Ovarian Cancer, Cells. 2020 Feb 25;9(3):527. (IF-6.6)
18.D. Rajagopalan, A.K. Pandey, M.C. Xiuzhen, K.K. Lee, S. Hora, Y. Zhang, B.H. Chua,H.S. Kwok, S.S. Bhatia, L.W. Deng, D.G. Tenen, D. Kappei, S. Jha, TIP60 represses telomerase expression by inhibiting Sp1 binding to the TERT promoter, PLoS Pathog. 2017 Oct 18;13(10):e1006681. (IF-6.8)
19.V. Pandey, M. Zhang, Q.-Y. Chong, M. You, A.R. Raquib, A.K. Pandey, D.-X. Liu, L. Liu, L. Ma, S. Jha, Z.S. Wu, T. Zhu, P.E. Lobie, Hypomethylation associated enhanced transcription of trefoil factor-3 mediates tamoxifen-stimulated oncogenicity of ER+ endometrial carcinoma cells, Oncotarget. 2017 Aug 24;8(44):77268-77291. (IF-5.3)
20.Y. Zhang, V.K. Subbaiah, D. Rajagopalan, C.Y. Tham, L.N. Abdullah, T.B. Toh, M. Gong, T.Z. Tan, S.P. Jadhav, A.K. Pandey, N. Karnani, E.K.-H. Chow, J.P. Thiery, S. Jha, TIP60 inhibits metastasis by ablating DNMT1−SNAIL2-driven epithelial-mesenchymal transition program, J Mol Cell Biol. 2016 Oct 1;8(5):384- 399. (IF- 6.2)
21.A.K. Pandey, Y. Zhang, S. Zhang, Y. Li, G. Tucker-Kellogg, H. Yang, S. Jha, TIP60- miR-22 axis as a prognostic marker of breast cancer progression, Oncotarget. 2015 Dec 1;6(38):41290-306. (IF-5.3)
22.S.G. Tattikota, T. Rathjen, S.J. McAnulty, H.-H. Wessels, I. Akerman, M. van de Bunt, J. Hausser, J.L.S. Esguerra, A. Musahl, A.K. Pandey, X. You, W. Chen, P.L. Herrera, P.R. Johnson,O’Carroll, L. Eliasson, M. Zavolan, A.L. Gloyn, J. Ferrer, R. Shalom-Feuerstein, D. Aberdam, M.N. Poy, Argonaute2 Mediates Compensatory Expansion of the Pancreatic β Cell, Cell Metab. 2014 Jan 7;19(1):122-34. (IF-27.2)
23.S.G. Tattikota, M.D. Sury, T. Rathjen, H.-H. Wessels, A.K. Pandey, X. You, C. Becker, Chen, M. Selbach, M.N. Poy, Argonaute2 Regulates the Pancreatic β-Cell Secretome, Mol Cell Proteomics. 2013 May;12(5):1214-25. (IF-5.9)
24.S. Vig, A.K. Pandey, G. Verma, M. Datta, C/EBPα mediates the transcriptional suppression of human calreticulin gene expression by TNFα, Int J Biochem Cell Biol. 2012 Jan;44(1):113-22 (IF-5.0)
25.K. Kaur, A.K. Pandey, S. Srivastava, A.K. Srivastava, M. Datta, Comprehensive miRNome and in silico analyses identify the Wnt signaling pathway to be altered in the diabetic liver, Mol Biosyst. 2011 Dec;7(12):3234-44. (IF-3.36)
26.A.K. Pandey, G. Verma, S. Vig, S. Srivastava, A.K. Srivastava, M. Datta, miR-29a levels are elevated in the db/db mice liver and its overexpression leads to attenuation of insulin action on PEPCK gene expression in HepG2 cells, Mol Cell Endocrinol. 2011 Jan 30;332(1-2):125-33 (IF-4.1)
27.A.K. Pandey, N. Munjal, M. Datta, Gene Expression Profiling and Network Analysis Reveals Lipid and Steroid Metabolism to Be the Most Favored by TNFα in HepG2 Cells, PLoS One. 2010 Feb 4;5(2):e9063. (IF-3.24)
28.A.K. Pandey, V. Bhardwaj, M. Datta, Tumour necrosis factor-α attenuates insulin action on phosphoenolpyruvate carboxykinase gene expression and gluconeogenesis by altering the cellular localization of Foxa2 in HepG2 cells, FEBS J. 2009 Jul;276(14):3757-69. (IF-5.54)
29.A.K. Pandey, P. Agarwal, K. Kaur, M. Datta, MicroRNAs in Diabetes: Tiny Players in Big Disease, Cell Physiol Biochem. 2009;23(4-6):221-32 (IF-5.14)

Book/Book Chapter/Patents/Peer Review Abstract
Book

1.Transcription and Translation Regulation in Health and Disease – Editors- Dr.Amit Kumar Pandey, Dr. Manoj Garg and Dr. Gautam Sethi, Elsevier Limited, Academic Press. ISBN- 9780323995214, January 2023

Book Chapters

•Sonali Pal, Manoj Garg and Amit Kumar Pandey. Biomarkers as putative therapeutic targets in colorectal cancer in book entitled Colon Cancer Diagnosis and Therapy Vol 1, Springer (Nature), 2020. ISBN 978303063368
•Shainan Hora*, Amit Kumar Pandey* and Sudhakar Jha (September 19th, 2018). Biomarker- Based Targeted Therapeutics, Neoplasm, IntechOpen, DOI: 10.5772/intechopen.78377. ISBN- 9781789237788
•Aishwarya Singh, Rachana Kumari, Anuradha Kirtonia, Gouri Pandya, Amit Kumar Pandey,* and Manoj Garg*. Current perspective of transcriptional regulators in human health and diseases. Transcription and Translation Regulation in Health and Disease, Elsevier Limited, Academic Press. ISBN- 9780323995214, January 2023.
•Sarika Bano, Mohammad Azam, Sanjay Kumar Dey, Amit Kumar Pandey*, Munindra Ruwali*. Recent insights into the role of phospholipase A2 enzymes in modulating cancer growth and development. Phospholipases in Physiology and Pathology, vol1. Elsevier Limited, Academic Press. ISBN- 9780443153136, 2023. *Joint corresponding author

Research Scholars

Student Details

ANKITA SANDIP PATEL

MS Student

Project Title: In-vitro and In-Silico assay to identify lncRNA-protein interaction in TNBC cell line.

PATIL PRATHAMESH VILAS

MS Student

Project Title: Unraveling the role of lncRNA in the Oral Squamous Cell Carcinoma.

SARDA AKASH RAMPRASAD

MS Student

Project Title:Exploring the role of DKK1 associated Circular RNA in Breast Cancer

SONJE ANUJA DILIP

MS Student

Project Title: Metabolomic and Lipidomic profiling of 3D model of drug resistant Triple Negative Breast Cancer.

TARANJEET KAUR

MS Student

Project Title: Lipidomic and metabolomic analysis in CRISPR-cas9 knockout p53 in ovarian cancer spheroids.